>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>5-Methoxytryptamine hydrochloride

5-Methoxytryptamine hydrochloride

Catalog No.GC64182

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5-Methoxytryptamine hydrochloride Chemical Structure

Cas No.: 66-83-1

Size 가격 재고 수량
250 mg
US$35.00
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500 mg
US$56.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

5-Methoxytryptamine hydrochloride, a metabolite of Melatonin, is a nonselective 5-HT receptor agonist. 5-Methoxytryptamine hydrochloride has no affinity for the 5-HT3 receptor. 5-Methoxytryptamine hydrochloride is also a potent antioxidant and has radioprotective action[1][2][3].

5-Methoxytryptamine hydrochloride induces a significant hyperglycemia above the dosage of 1 mg/kg in rats[1].

[1]. J Yamada, et al. Hyperglycemia induced by the 5-HT receptor agonist, 5-methoxytryptamine, in rats: involvement of the peripheral 5-HT2A receptor. Eur J Pharmacol. 1997 Apr 4;323(2-3):235-40. [2]. S Bayari, et al. Fourier transform infrared spectra and molecular structure of 5-methoxytryptamine, N-acetyl-5-methoxytryptamine and N-phenylsulfonamide-5-methoxytryptamine. Spectrochim Acta A Mol Biomol Spectrosc. 2003 Apr;59(6):1255-63.
[3]. D A Craig, et al. 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum. Naunyn Schmiedebergs Arch Pharmacol. 1990 Jul;342(1):9-16.

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