BCI hydrochloride (Synonyms: (E)-BCI hydrochloride) |
| Catalog No.GC65025 |
BCI((E)-BCI) 염산염은 DUSP6(이중 특이성 포스파타제 6) 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 95130-23-7
Sample solution is provided at 25 µL, 10mM.
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BCI hydrochloride ((E)-BCI hydrochloride) is an allosteric inhibitor of dual specificity phosphatase (DUSP). BCI hydrochloride specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI hydrochloride does not inhibit DUSP5[1].
[1]. Korotchenko VN, et al. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem. 2014 Jul 7;15(10):1436-45.
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