Boc-AEVD-CHO (trifluoroacetate salt) (Synonyms: Boc-Ala-Glu-Val-Asp-CHO) |
| Catalog No.GC40149 |
Boc-AEVD-CHO is an inhibitor of caspase-8 (Ki = 1.6 nM) that also inhibits caspase-1, -3, -6, and -9 (Kis = 10,000, 375, 438, 425, and 320 nM, respectively).
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Boc-AEVD-CHO is an inhibitor of caspase-8 (Ki = 1.6 nM) that also inhibits caspase-1, -3, -6, and -9 (Kis = 10,000, 375, 438, 425, and 320 nM, respectively). Boc-AEVD-CHO has been used to study the potential interference of caspase-8 activity in micronuclei detection. It inhibits apoptosis induced by the aneugen nocodazole in isolated human peripheral blood mononuclear cells (PBMCs) when used at a concentration of 300 µM.
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