H-D-Phe-Pip-Arg-pNA hydrochloride (Synonyms: H-D-Phe-Pip-Arg-pNA, D-Phe-Piperidinecarbonyl-Arg-p-nitroanilide) |
| Catalog No.GC60187 |
발색 기질인 H-D-Phe-Pip-Arg-pNA(S-2238) 염산염은 트롬빈의 천연 기질인 피브리노겐 A 알파 사슬의 N-말단 부분 다음에 패턴화됩니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 160192-34-7
Sample solution is provided at 25 µL, 10mM.
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H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform[1][2].
[1]. Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647. [2]. van Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353.
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