MC-Val-Ala-PBD (Synonyms: SGD-1910 ) |
| Catalog No.GC39403 |
MC-Val-Ala-PBD는 항종양 항생제인 pyrrolobenzodiazepine(PBD, cytotoxic DNA crosslinking)을 사용하여 ADC용 약물-링커 접합체이며 절단 가능한 링커 MC-Val-Ala를 통해 연결됩니다.
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Cas No.: 1342820-51-2
Sample solution is provided at 25 µL, 10mM.
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MC-Val-Ala-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala[1].
[1]. Jeffrey SC, et al. A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology. Bioconjug Chem. 2013 Jul 17;24(7):1256-63.
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