UNC6852 |
Catalog No.GC39588 |
UNC6852는 PROTAC을 기반으로 하는 선택적 폴리콤 억제 복합체 2(PRC2) 분해제이며 EED에 대한 IC50이 247nM인 EED(배아 외배엽 발달) 리간드와 von Hippel-Lindau 리간드를 포함합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2688842-08-0
Sample solution is provided at 25 µL, 10mM.
UNC6852 is a selective rolycomb repressive complex 2 (PRC2) degrader based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a VHL ligand, with an IC50 of 247 nM for EED[1].
[1]. Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27(1):47-56.e15.
Average Rating: 5
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