UNC6852 |
| カタログ番号GC39588 |
UNC6852 は、PROTAC に基づく選択的ポリコーム抑制複合体 2 (PRC2) 分解剤であり、EED (胚性外胚葉発生) リガンドと von Hippel-Lindau リガンドを含み、EED の IC50 は 247 nM です。
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Cas No.: 2688842-08-0
Sample solution is provided at 25 µL, 10mM.
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UNC6852 is a selective rolycomb repressive complex 2 (PRC2) degrader based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a VHL ligand, with an IC50 of 247 nM for EED[1].
[1]. Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27(1):47-56.e15.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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