EMAC10101d |
| Catalog No.GC19576 |
EMAC10101d는 8.1nM의 Ki로 hCA II 억제제에 대해 강력하고 선택적입니다.
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Cas No.: 2561476-24-0
Sample solution is provided at 25 µL, 10mM.
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Compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an inhibitory activity in the low nanomolar range.
Reference:
[1]. Meleddu R , Distinto S , Cottiglia F , et al. New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII[J]. ACS Medicinal Chemistry Letters, 2020, XXXX(XXX).
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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