C18 D-threo Ceramide (d18:1/18:0) (Synonyms: D-threo Cer(d18:1/18:0), D-threo Ceramide (d18:1/18:0), N-octadecanoyl-D-threo-Sphingosine, N-stearoyl-D-threo-Sphingosine) |
| Catalog No.GC48425 |
A synthetic ceramide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 252039-53-5
Sample solution is provided at 25 µL, 10mM.
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C18 D-threo Ceramide (d18:1/18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1 It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 16.6 µM.2 [Matreya, LLC. Catalog No. 1855]
1.Koolath, S., Murai, Y., Suga, Y., et al.Chiral combinatorial preparation and biological evaluation of unique ceramides for inhibition of sphingomyelin synthaseChirality32(3)308-313(2019) 2.Usta, J., El Bawab, S., Roddy, P., et al.Structural requirements of ceramide and sphingosine based inhibitors of mitochondrial ceramidaseBiochemistry40(32)9657-9668(2001)
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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