N-desethyl Brinzolamide (oxalate) (Synonyms: AL 8520) |
| Catalog No.GC49210 |
An active metabolite of brinzolamide
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Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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N-desethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1 It inhibits CAII and CAIV activities (IC50s = 1.28 and 128 nM, respectively).
1.Kim, C.-Y., Whittington, D.A., Chang, J.S., et al.Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IVJ. Med. Chem.45(4)888-893(2002)
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