Albendazole sulfone-d3 (Synonyms: ABZ-SO2-d3, ABZ-SOO-d3) |
| Catalog No.GC49773 |
An internal standard for the quantification of albendazole sulfone
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1448345-60-5
Sample solution is provided at 25 µL, 10mM.
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Albendazole sulfone-d3 is intended for use as an internal standard for the quantification of albendazole sulfone by GC- or LC-MS. Albendazole sulfone is an active metabolite of the benzimidazole anthelmintic albendazole .1,2 It inhibits spore formation of E. hellem, E. cuniculi, and E. intestinalis in vitro (IC90s = <0.0001, <0.001, and <0.1 µg/ml, respectively).2
1.BaliharovÁ, V., VelÍk, J., FimanovÁ, K., et al.Inhibitory effect of albendazole and its metabolites on cytochromes P450 activities in rat and mouflon in vitroPharmacol. Rep.5797-106(2005) 2.Ridoux, O., and Drancourt, M.In vitro susceptibilities of the microsporidia Encephalitozoon cuniculi, Encephalitozoon hellem, and Encephalitozoon intestinalis to albendazole and its sulfoxide and sulfone metabolitesAntimicrob. Agents and Chemother.42(12)3301-3303(1998)
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