SJFδ |
Catalog No.GC33238 |
SJF&델타; von Hippel-Lindau 리간드를 기반으로 하는 10개 원자 링커 PROTAC입니다. SJF&델타; 46.17 nM의 DC50으로 p38δ를 분해하지만 p38α, p38β 또는 p38γ는 분해하지 않습니다.
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Cas No.: 2254609-23-7
Sample solution is provided at 25 µL, 10mM.
SJFδ is a 10-atom linker PROTAC. SJFδ degrades p38α with a DC50 of 46.17 nM, but does not degrade p38α, p38β, or p38γ[1].
[1]. Smith BE, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019 Jan 10;10(1):131.
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