CDD0102 (CDD0102A) (Synonyms: CDD0102A) |
Catalog No.GC31255 |
CDD0102(CDD0102A)는 강력한 M1 무스카린 수용체 작용제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 146422-58-4
Sample solution is provided at 25 µL, 10mM.
CDD0102 is a potent M1 Muscarinic receptor agonist.
CDD0102 (CDD-0102) is an efficacious muscarinic agonist in cell lines expressing M1 receptors. CDD0102 displays much lower activity at M3 and M5 receptors[1].
After i.p. injections, CDD0102 (CDD-0102) crosses the blood-brain barrier (BBB) in a dose-dependent manner. In toxicological studies, the LD50 of CDD0102 is 190 mg/kg following i.p. injections and greater than 1,000 mg/kg following oral administration. In follow-up studies, after oral administration at a dose of 10 mg/kg, CDD0102 fully reverses memory deficits associated with IgG-192 saporin administration. Again, no side effects are observed at this dose[1].
[1]. Messer WS Jr. The utility of muscarinic agonists in the treatment of Alzheimer's disease. J Mol Neurosci. 2002 Aug-Oct;19(1-2):187-93.
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(Based on Reviews and 19 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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