CX-157 |
| Catalog No.GC31155 |
CX-157은 19.3ng/mL의 EC50을 갖는 모노아민 산화효소-A(MAO-A)의 가역적 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 205187-53-7
Sample solution is provided at 25 µL, 10mM.
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CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.
CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL. CX-157 is an investigational compound currently in development for the treatment of major depressive disorder (MDD). Mechanistic studies in animals have shown that CX-157 acts to inhibit MAO-A activity in a reversible and competitive manner, elevating brain levels of monoamine neurotransmitters[1].
[1]. Fowler JS, et al. Reversible inhibitors of monoamine oxidase-A (RIMAs): robust, reversible inhibition of human brain MAO-A by CX157. Neuropsychopharmacology. 2010 Feb;35(3):623-31.
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