>>Labeling & Detection>> Cyanine Dyes>>Cy5.5 NHS ester (non-sulfonated)

Cy5.5 NHS ester (non-sulfonated)

Catalog No.GC11653

Cy5.5-NHS 에스터는 펩타이드, 단백질 및 올리고뉴클레오티드의 아미노기를 라벨링하기 위한 근적외선 아민 반응성 염료입니다.

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Cy5.5 NHS ester (non-sulfonated) Chemical Structure

Cas No.: 1469277-96-0

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$373.00
재고 있음
5mg
US$149.00
재고 있음
25mg
US$283.00
재고 있음
100mg
US$1,139.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 2 publications

Description Protocol Chemical Properties Product Documents Related Video Related Products

Cy5.5-NHS ester is a near-infrared amine reactive dye for labeling amino groups of peptides, proteins and oligonucleotides. Cy5.5-NHS ester is suitable for fluorescence analysis when the background fluorescence interferes. It can also be used for in vivo imaging experiments. Cy5.5-NHS ester can be dissolved in DMF and DMSO, the maximum excitation light and maximum emission light are around 675 nm and 693 nm, respectively.[1]

In vitro and in vivo experiment indicated that Cy5.5-NHS ester is a nice near-infrared fluorescent dye, which could be used for tumor targeting as well as examining the effect of D-glucose or L-glucose on 2-NBDG accumulation. Moreover, Cy5.5-NHS ester reacts swiftly that the tumor/muscle contrast could be clearly visualized from 30 min up to 24 h pi of 0.5 nmol Cy5.5-NHS. The tumor uptake of Cy5.5-NHS reached a maximum 30 minutes pi. [2]

References:
[1].Ju HR, et al. Non-invasive optical imaging of cathepsin B with activatable fluorogenic nanoprobes in various metastatic models. Biomaterials. 2014. 35: 2302-2311.
[2].Zhen C. et al. Near-Infrared Fluorescent Deoxyglucose Analog for Tumor Optical Imaging in Cell Culture and in Living Mice. Bioconjug Chem. 2006 ; 17(3): 662–669.

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