Digitoxigenin (Synonyms: Cerberigenin, (+)-Digitoxigenin, Echujetin, Evonogenin, NSC 407806, Thevetigenin, Δ20:22-3,14,21-Trihydroxynorcholenic acid lactone) |
| Catalog No.GC41485 |
Digitoxigenin is a cardenolide and aglycone constituent of digitoxin, an extract from the foxglove plant, D.
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Cas No.: 143-62-4
Sample solution is provided at 25 µL, 10mM.
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Digitoxigenin is a cardenolide and aglycone constituent of digitoxin, an extract from the foxglove plant, D. purpurea. It elicits cardiac contraction and cardiotonic effects by inhibiting the Na+/K+ ATPase via binding at the digitalis receptor site with nanomolar potency. Digitoxigenin is highly cytotoxic, inhibiting Na+/K+ ATPase-dependent protein synthesis, and has been examined for use as an antitumor compound.
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