DMNPE-4 AM-caged-calcium |
Catalog No.GC50302 |
EGTA의 광불안정성 유사체인 DMNPE-4 AM-케이지드-칼슘은 pH 7.2 및 pH 7.4에서 Ca2+에 대한 Kd가 각각 48nM 및 19nM인 매우 효과적인 Ca2+ 선택적 케이지입니다.
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Cas No.: 2253744-58-8
Sample solution is provided at 25 µL, 10mM.
Caged calcium (Kd values are 48 and 19 nM at pH 7.2 and 7.4, respectively; Kd after uncaging = 2 mM). Selective over Mg2+ (Kd =10 mM). Rapid and efficient calcium release upon photolysis at 350 nm. Can also be used for two-photon uncaging. Extinction coefficient of 5120 M-1 cm-1, quantum yield 0.09. Cell permeable.
Wang et al (2015) Spontaneous activity of cochlear hair cells triggered by fluid secretion mechanism in adjacent support cells Cell 163 1348 PMID:26627734 |Gordon et al (2008) Brain metabolism dictates the polarity of astrocyte control over arterioles. Nature 456 745 PMID:18971930 |Ellis-Davies et al (2006) Tuning caged calcium: photolabile analogues of EGTA with improved optical and chelation properties. Cell Calcium 39 75 PMID:16303177
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