ent-8-iso-15(S)-Prostaglandin F2α (Synonyms: ent-15-epi-F2t-Isoprostane, ent-8-iso-15-epi-PGF2α) |
Catalog No.GC40590 |
Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 214748-66-0
Sample solution is provided at 25 µL, 10mM.
Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.
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