Fullerene-C60 |
| Catalog No.GC61661 |
탄소나노화합물의 대표적인 물질인 Fullerene-C60은 독특한 물리화학적 특성으로 인해 광역학 치료에 유망한 물질로 제시되고 있다. Fullerene-C60은 전자와 에너지 전달의 분자내 역학을 조사합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 99685-96-8
Sample solution is provided at 25 µL, 10mM.
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Fullerene-C60, a representative of carbon nanocompounds, is suggested to be promising agent for application in photodynamic therapy due to its unique physicochemical properties. Fullerene-C60 probes the intramolecular dynamics of its electron and energy transfer[1].
High affinity of fullerene core for electron donors determines its ability to be a scavenger of free radicals. On the other hand, C60 molecule is able to absorb effectively UV and visible light with further transition to the first singlet excited state, then to a long-lived triplet excited state and subsequent energy transfer to molecular oxygen-yielding singlet oxygen with quantum yield close to 100%[1].
[1]. D Franskevych,et al. Fullerene C 60 Penetration into Leukemic Cells and Its Photoinduced Cytotoxic Effects. Nanoscale Res Lett.2017 Dec;12(1):40.
| Cas No. | 99685-96-8 | SDF | |
| Canonical SMILES | C1(C2=C3C4=C15)=C(C6=C7C2=C8C(C(C9=C%10%11)=C%12C%10=C%13C%14=C%15%16)=C7C%17=C9C%18=C%19C%17=C6C%20=C%21C%19=C%22C%23=C%18C%11=C%14C%23=C%24C%16=C%25C%26=C%27C4=C%28C%29=C3C8=C%12C%29=C%13C%15=C%28%26)C%20=C%30C5=C%27C%31=C%25C%24=C%22C%21=C%30%31 | ||
| Formula | C60 | M.Wt | 720.64 |
| Solubility | Water: < 0.1 mg/mL (ultrasonic) (insoluble); DMSO: < 1 mg/mL (ultrasonic) (insoluble or slightly soluble) | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 1.3877 mL | 6.9383 mL | 13.8766 mL |
| 5 mM | 0.2775 mL | 1.3877 mL | 2.7753 mL |
| 10 mM | 0.1388 mL | 0.6938 mL | 1.3877 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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