Ibrutinib deacryloylpiperidine |
| Catalog No.GC60197 |
이브루티닙 디아크릴로일피페리딘(IBT4A)은 이브루티닙의 불순물입니다. 이브루티닙은 IC50이 0.5nM인 선택적 비가역적 Btk 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 330786-24-8
Sample solution is provided at 25 µL, 10mM.
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Ibrutinib deacryloylpiperidine (IBT4A) is an impurity of Ibrutinib[1]. Ibrutinib is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[2].
[1]. Somana Siva Prasad, et al. A QUALITY BY DESIGN APPROACH FOR DEVELOPMENT OF SIMPLE AND ROBUST REVERSED PHASE STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF IBRUTINIB AND ITS IMPURITIES. [2]. Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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