Cyclic MKEY |
| Catalog No.GC35777 |
Cyclic MKEY는 CXCL4-CCL5 이종이량체 형성의 합성 고리형 펩티드 억제제로, 염증을 매개하여 죽상동맥경화증 및 대동맥류 형성을 방지합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 934385-55-4
Sample solution is provided at 25 µL, 10mM.
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Cyclic MKEY is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation. Cyclic MKEY also protects against stroke-induced brain injury in mice[1][2]. CXCL4-CCL5 heterodimer formation[1]
[1]. Fan Y,et al. MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice. J Am Heart Assoc. 2016 Sep 15;5(9). pii: e003615. [2]. Iida Y, et al. Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression. Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):718-26.
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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