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SPL-410

Catalog No.GC37675

SPL-410은 9 nM의 IC50을 갖는 경구 활성, 매우 강력하고 선택적인 하이드록시에틸아민 기반 SPPL2a(Signal Peptide Peptidase Like 2a) 억제제입니다.

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SPL-410 Chemical Structure

Cas No.: 2351886-00-3

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM[1]. IC50: 9 nM (SPPL2a)[1].

[1]. Velcicky J, et al. Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors. ACS Med Chem Lett. 2019 May 23;10(6):887-892.

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Average Rating: 5 ★★★★★ (Based on Reviews and 27 reference(s) in Google Scholar.)

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