Eupatorin (Synonyms: NSC 106402) |
| Catalog No.GC36017 |
자연적으로 발생하는 플라본인 유파토린은 세포 주기의 G2-M 단계에서 세포를 정지시키고 다중 카스파제의 활성화, 시토크롬 c의 미토콘드리아 방출 및 폴리(ADP-리보스) 중합효소 절단을 포함하는 세포자멸사 세포사를 유도합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 855-96-9
Sample solution is provided at 25 µL, 10mM.
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Eupatorin, a naturally occurring flavone, arrests cells at the G2-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c and poly(ADP-ribose) polymerase cleavage[1].
[1]. EstÉvez S, et al. Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen-activated protein kinase pathway. PLoS One. 2014 Nov 12;9(11):e112536.
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