Glucose-conjugated MGMT inhibitor |
| Catalog No.GC36153 |
Glucose-conjugated MGMT inhibitor는 강력한 O6-methylguanine-DNAmethyl-transferase(MGMT) 억제제로, IC50이 시험관 내에서 32nM(세포 추출물)이고 HeLa S3 세포에서 10nM입니다.
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Cas No.: 382607-78-5
Sample solution is provided at 25 µL, 10mM.
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Glucose-conjugated MGMT inhibitor is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. MGMT|32 nM (IC50)
Glucose-conjugated MGMT inhibitor (O6BTG-octylglucoside) is a potent and non-toxic MGMT inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells[1].
[1]. Jost Reinhard, et al. Inactivation of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors. Int.J.Cancer. (2001) 93,373-379.
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