Antibiotic PF 1052 |
| Catalog No.GC45383 |
항생제 PF 1052는 천연물 라이브러리에서 추출한 항생제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 147317-15-5
Sample solution is provided at 25 µL, 10mM.
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Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively), among others.1 It inhibits neutrophil migration in a wound assay using zebrafish larvae expressing GFP-labeled neutrophils, reducing pseudopodia formation and inducing rounding of neutrophils.2 Antibiotic PF 1052 is selective for neutrophil migration over macrophage migration in zebrafish larvae. It also inhibits the migration of murine neutrophils when used at concentrations of 10 and 20 μM.
References
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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