GSK-2793660 |
| Catalog No.GC62634 |
GSK-2793660(유리 염기)은 카텝신 C(CTSC)의 비가역적 경구 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1613458-70-0
Sample solution is provided at 25 µL, 10mM.
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GSK-2793660 is an oral, irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 can be used for the research of bronchiectasis[1][2].
GSK-2793660 is a cathepsin C (also known as dipeptidyl peptidase I enzyme) inhibitor for the reaearch of cystic fibrosis, non-cystic fibrosis bronchiectasis, anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis and bronchiectasis[1].
[1]. Szcze?niak P, et al. The Synthesis of α,α-Disubstituted α-Amino Acids via Ichikawa Rearrangement. J Org Chem. 2016 Feb 5;81(3):1057-74.
[2]. Miller BE, et al. Epithelial desquamation observed in a phase I study of an oral cathepsin C inhibitor (GSK2793660). Br J Clin Pharmacol. 2017 Dec;83(12):2813-2820.
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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