H-Gly-Pro-Arg-Pro-OH (acetate) (Synonyms: GPRP) |
| Catalog No.GC18983 |
H-Gly-Pro-Arg-Pro-OH(아세테이트)(Gly-Pro-Arg-Pro acetate)는 섬유소원과 혈소판막 당단백질 IIb/IIIa 복합체(GPIIb/IIIa)의 상호작용을 억제하는 섬유소 중합 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 157009-81-9
Sample solution is provided at 25 µL, 10mM.
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H-Gly-Pro-Arg-Pro-OH (GPRP) is a peptide corresponding partly to the amino terminus of the Aα chain and Bβ chain of fibrin. It inhibits the spontaneous polymerization of fibrin monomers and also inhibits ADP-induced platelet aggregation (IC50 = 3 mM). GPRP binds to the fibrinogen D domain, inhibiting the ability of fibrinogen to bind to the platelet membrane glycoprotein GPIIb/IIIa.
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