H-Gly-Pro-Arg-Pro-OH (acetate) (Synonyms: GPRP) |
| Katalog-Nr.GC18983 |
H-Gly-Pro-Arg-Pro-OH (Acetat) (Gly-Pro-Arg-Pro-Acetat) ist ein Fibrinpolymerisationsinhibitor, der die Wechselwirkung von Fibrinogen mit dem PlÄttchenmembran-Glykoprotein IIb/IIIa-Komplex (GPIIb/IIIa) hemmt.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 157009-81-9
Sample solution is provided at 25 µL, 10mM.
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H-Gly-Pro-Arg-Pro-OH (GPRP) is a peptide corresponding partly to the amino terminus of the Aα chain and Bβ chain of fibrin. It inhibits the spontaneous polymerization of fibrin monomers and also inhibits ADP-induced platelet aggregation (IC50 = 3 mM). GPRP binds to the fibrinogen D domain, inhibiting the ability of fibrinogen to bind to the platelet membrane glycoprotein GPIIb/IIIa.
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