Hecogenin Acetate (Synonyms: NSC 15489) |
| Catalog No.GC43808 |
Hecogenin acetate는 스테로이드성 사포게닌-아세틸화되어 항염증 및 항통각수용성이 있다.
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Cas No.: 915-35-5
Sample solution is provided at 25 µL, 10mM.
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Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties. It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml). Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine , and prostaglandin E2 in mice. It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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