Helichrysetin |
| Catalog No.GC64662 |
Helichrysum odoratissimum의 꽃에서 분리된 Helichrysetin은 ID2(DNA 결합 2 억제제) 억제제이며 DCIS(ductal carcinoma in situ) 형성을 억제합니다. Helichrysetin은 세포 성장에 대한 강력한 억제 효과를 가지고 있으며 A549 세포에서 apoptosis를 유도할 수 있습니다.
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Cas No.: 62014-87-3
Sample solution is provided at 25 µL, 10mM.
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Helichrysetin, isolated from the flowers of Helichrysum odoratissimum, is an ID2 (inhibitor of DNA binding 2) inhibitor, and suppresses DCIS (ductal carcinoma in situ) formation. Helichrysetin possess strong inhibitory effects on cell growth and is capable of inducing apoptosis in A549 cells[1][2].
[1]. Liu Y, et al. ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness. Breast Cancer Res Treat. 2019 May;175(1):77-90.
[2]. Ho YF, et al. Induction of apoptosis and cell cycle blockade by helichrysetin in a549 human lung adenocarcinoma cells. Evid Based Complement Alternat Med. 2013;2013:857257.
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