Helichrysetin |
| Katalog-Nr.GC64662 |
Helichrysetin, isoliert aus den BlÜten von Helichrysum odoratissimum, ist ein ID2 (Inhibitor of DNA Binding 2)-Inhibitor und unterdrÜckt die Bildung von DCIS (Ductus Carcinoma in situ). Helichrysetin besitzt starke inhibitorische Wirkungen auf das Zellwachstum und ist in der Lage, Apoptose in A549-Zellen zu induzieren.
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Cas No.: 62014-87-3
Sample solution is provided at 25 µL, 10mM.
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Helichrysetin, isolated from the flowers of Helichrysum odoratissimum, is an ID2 (inhibitor of DNA binding 2) inhibitor, and suppresses DCIS (ductal carcinoma in situ) formation. Helichrysetin possess strong inhibitory effects on cell growth and is capable of inducing apoptosis in A549 cells[1][2].
[1]. Liu Y, et al. ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness. Breast Cancer Res Treat. 2019 May;175(1):77-90.
[2]. Ho YF, et al. Induction of apoptosis and cell cycle blockade by helichrysetin in a549 human lung adenocarcinoma cells. Evid Based Complement Alternat Med. 2013;2013:857257.
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