Hematoporphyrin monomethyl ether |
| Catalog No.GC63902 |
2세대 포르피린 관련 감광제인 헤마토포르피린 모노메틸 에테르는 단일 형태, 높은 일중항 산소 수율, 높은 선택성, 낮은 독성을 특징으로 하여 폐암을 비롯한 다양한 종양의 진단 및 치료에 널리 사용되고 있으며, 방광암, 그리고 nevus flammeus 및 뇌 신경교종.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 148471-91-4
Sample solution is provided at 25 µL, 10mM.
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Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and treatment of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma[1].
Hematoporphyrin monomethyl ether (HMME) is a novel and promising porphyrin-related photosensitizer for photodynamic therapy (PDT). HMME-PDT can induce cell deaththrough both necrosis and apoptosis in HeLa cells. ROS, such as singlet oxygen and hydroxyl radical, generated in HeLa cells play a decisive role in HMME-PDT-induced cell death[2].
[1]. Ding X, et al. Hematoporphyrin monomethyl ether photodynamic damage on HeLa cells by means of reactive oxygen species production and cytosolic free calcium concentration elevation. Cancer Lett. 2004;216(1):43-54.
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