Hematoporphyrin monomethyl ether |
| Katalog-Nr.GC63902 |
HÄmatoporphyrinmonomethylether, die zweite Generation von Porphyrin-verwandten Photosensibilisatoren, zeichnet sich durch seine Einzelform, hohe Ausbeute an Singulett-Sauerstoff, hohe SelektivitÄt und geringe ToxizitÄt aus, die bei der Diagnose und Behandlung verschiedener Tumoren, einschließlich Lungenkrebs, weit verbreitet ist. Blasenkrebs und NÄvus flammeus und Hirngliom.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 148471-91-4
Sample solution is provided at 25 µL, 10mM.
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Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and treatment of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma[1].
Hematoporphyrin monomethyl ether (HMME) is a novel and promising porphyrin-related photosensitizer for photodynamic therapy (PDT). HMME-PDT can induce cell deaththrough both necrosis and apoptosis in HeLa cells. ROS, such as singlet oxygen and hydroxyl radical, generated in HeLa cells play a decisive role in HMME-PDT-induced cell death[2].
[1]. Ding X, et al. Hematoporphyrin monomethyl ether photodynamic damage on HeLa cells by means of reactive oxygen species production and cytosolic free calcium concentration elevation. Cancer Lett. 2004;216(1):43-54.
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