IACS-8803 disodium |
| Catalog No.GC62586 |
IACS-8803 이나트륨은 매우 강력한 고리형 디뉴클레오티드 STING 작용제입니다. IACS-8803 이나트륨은 강력한 전신 항종양 효능을 가지고 있습니다.
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Cas No.: 2243079-36-7
Sample solution is provided at 25 µL, 10mM.
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IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1].
IACS-8803 (10 µg; intra-tumoral injection) shows superior antitumor activity in mice bearing bilateral B16-OVA melanomas[1].
[1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.
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