Lobaplatin |
| Catalog No.GC61000 |
Lobaplatin(D-19466)은 백금(II) 착물의 부분입체학적 혼합물입니다. Lobaplatin은 G1 및 G2/M 단계에서 세포 주기를 정지시킵니다. Lobaplatin은 caspase와 Bax의 발현을 증가시켜 Bcl-2의 발현을 감소시켜 세포자살을 유도한다. 로바플라틴은 암 연구에 사용할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 135558-11-1
Sample solution is provided at 25 µL, 10mM.
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Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes. Lobaplatin (D-19466) shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2].
[1]. Cao H, et al. Lobaplatin Inhibits Prostate Cancer Proliferation and Migration Through Regulation of BCL2 and BAX. Dose Response. 2019 Jun 5;17(2):1559325819850981. [2]. McKeage MJ, et al. Lobaplatin: a new antitumour platinum drug. Expert Opin Investig Drugs. 2001 Jan;10(1):119-28.
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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