Lobaplatin |
| Katalog-Nr.GC61000 |
Lobaplatin (D-19466) ist ein diastereometrisches Gemisch aus Platin(II)-Komplexen. Lobaplatin hÄlt den Zellzyklus in der G1- und G2/M-Phase an. Lobaplatin induziert Apoptose, indem es die Expression von Caspase und Bax erhÖht und die Expression von Bcl-2 verringert. Lobaplatin kann fÜr die Krebsforschung verwendet werden.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 135558-11-1
Sample solution is provided at 25 µL, 10mM.
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Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes. Lobaplatin (D-19466) shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2].
[1]. Cao H, et al. Lobaplatin Inhibits Prostate Cancer Proliferation and Migration Through Regulation of BCL2 and BAX. Dose Response. 2019 Jun 5;17(2):1559325819850981. [2]. McKeage MJ, et al. Lobaplatin: a new antitumour platinum drug. Expert Opin Investig Drugs. 2001 Jan;10(1):119-28.
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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