>>Infectious Disease>> Fungal Diseases>> Candidiasis>>Maculosin

Maculosin (Synonyms: Cyclo(L-Pro-L-Tyr))

Catalog No.GC18331

Maculosin은 Alternaria alternata의 점박이 개풀에 대한 숙주 특이적 식물 독소입니다. Maculosin은 녹농균(Pseudomonas aeruginosa)에 의한 세포 간 통신에 관여하는 정족수 감지 분자입니다. Maculosin은 또한 Lactobacillus reuteri에서 독성 유전자 발현을 조절하는 신호 분자로 작용합니다. Maculosin은 항산화, 항암 및 무독성 특성을 나타냅니다. Maculosin은 48.90 μg/mL의 IC50으로 인간 간암 세포주에 대한 세포독성 활성을 나타냅니다.

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Maculosin Chemical Structure

Cas No.: 74345-23-6,4549-02-4

Size 가격 재고 수량
5mg
US$111.00
재고 있음
25mg
US$356.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products
Maculosin is a diketopiperazine metabolite produced by A. alternata, L. capsici, Streptomyces, and the Gram-negative, nonobligate predator bacterial strain 679-2. It acts as a host-specific phytotoxin, inducing formation of weeping necrotic lesions in leaves of spotted knapweed (C. maculosa) when used at a concentration of 10 μM. Maculosin reduces the growth of the plant pathogenic bacteria X. axonopodis and R. solanacearum (MICs = 31.25 μg/ml) as well as the pathogenic oomycetes P. cactorum, P. capsici, P. cinnamomi, P. infestans, and P. ultimum when used at concentrations ranging from 10 to 100 mg/ml. Maculosin also inhibits the growth of M. luteus, M. smegmatis, S. cerevisiae, C. albicans, C. neoformans, and A. niger when used in combination with pyrrolnitrin or banegasin.

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Average Rating: 5 ★★★★★ (Based on Reviews and 19 reference(s) in Google Scholar.)

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