Mal-PEG4-VC-PAB-DMEA-PNU-159682 |
| Catalog No.GC63503 |
ADC용 약물-링커 접합체인 Mal-PEG4-VC-PAB-DMEA-PNU-159682는 ADC 링커 Mal-PEG4-VC-PAB 및 강력한 ADC 세포독소 DMEA-PNU-159682로 구성됩니다. DMEA-PNU-159682에는 간 마이크로솜 및 ADC 세포독소 PNU-159682에서 유래한 네모루비신(MMDX)의 대사 산물이 포함됩니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2259318-52-8
Sample solution is provided at 25 µL, 10mM.
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Mal-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].
[1]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1
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