MIF-1 TFA (Synonyms: Pro-Leu-Gly-NH2 TFA; Melanostatin TFA) |
| Catalog No.GC61955 |
내인성 뇌 펩티드인 MIF-1 TFA(멜라노스타틴)는 강력한 도파민 수용체 알로스테릭 조절제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 35240-69-8
Sample solution is provided at 25 µL, 10mM.
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MIF-1 TFA, an antibiotic with melanin synthesis inhibitory activity, strongly inhibits melanin formation in Streptomyces bikiniensis NRRLB-1049 and B16 melanoma cells[1].
MIF-1 (Melanostatin, 1 µM) provoked a reversible hyperpolarization and a suppression of spontaneous action potentials[2].
References:
[1]. PRODUCTION, et al. MELANOSTATIN, A NEW MELANIN SYNTHESIS INHIBITOR. The Journal of Antibiotics. 1991.
[2]. J A Valentijn, et al. Melanostatin (NPY) inhibited electrical activity in frog melanotrophs through modulation of K+, Na+ and Ca2+ currents. J Physiol . 1994 Mar 1;475(2):185-95.
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