N33-TEG-COOH (N3-TEG-COOH) |
| Catalog No.GC32955 |
N33-TEG-COOH(N3-TEG-COOH)(N3-TEG-COOH)는 PROTAC 합성에 사용할 수 있는 PEG 기반 PROTAC 링커입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 201467-81-4
Sample solution is provided at 25 µL, 10mM.
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N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units.
N33-TEG-COOH is a long linker extracted from Reference PMID: 26035625, Compound 7. A PROTAC is a heterobifunctional compound that contains two ligands connected by a linker unit. One ligand binds an E3 ubiquitin ligase protein, while the other ligand binds to the target protein of interest, thereby bringing the ligase and the target in close proximity[1].
[1]. Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.
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