Naled (Synonyms: Bromchlophos) |
Catalog No.GC47742
One-Click Copy Product Info
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An organophosphate insecticide and acaricide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 300-76-5
Sample solution is provided at 25 µL, 10mM.
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Naled is an organophosphate insecticide and acaricide that inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).1 It reduces the number of A. sollicitans mosquitos by 97% after one hour when aerially applied at a concentration of 0.1 pounds per acre.2 Naled (125 ppm AI) induces 100 and 64% mortality of T. telarius adults and immature mites, respectively, in an immediate contact toxicity test but does not induce mortality in mite eggs.3 It is toxic to rats with an LD50 value of 250 mg/kg.4 Formulations containing naled have been used in the control of mosquitoes in public areas and of crop-damaging insects in agriculture.
1.Herzsprung, P., Weil, L., and Niessner, R.Measurement of bimolecular rate constants ki of the cholinesterase inactivation reaction by 55 insecticides and of the influence of various pyridiniumoximes on kiInt. J. Eniviron. Anal. Chem.47(3)181-200(1992) 2.Knapp, F.W., and Rogers, C.E.Low volume aerial insecticide application for the control of Aedes sollicit and walkerMosquito News28(4)535-540(1968) 3.Mailloux, M., and Morrison, F.O.The effects of acaricides on the developmental stages of the two-spotted spider mite, Tetranychu telariusJ. Econ. Entomol.55(4)479-483(1962) 4.Gaines, T.B.Acute toxicity of pesticidesToxicol. Appl. Pharmacol.14(3)515-534(1969)
| Cas No. | 300-76-5 | SDF | |
| Synonyms | Bromchlophos | ||
| Canonical SMILES | BrC(Cl)(Cl)C(Br)OP(OC)(OC)=O | ||
| Formula | C4H7Br2Cl2O4P | M.Wt | 380.8 |
| Solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:4): 0.20 mg/ml | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.6261 mL | 13.1303 mL | 26.2605 mL |
| 5 mM | 525.2 μL | 2.6261 mL | 5.2521 mL |
| 10 mM | 262.6 μL | 1.313 mL | 2.6261 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)