P7C3-A20 |
| Catalog No.GC19274 |
P7C3-A20은 강력한 전신경성 및 신경보호 활성을 갖는 P7C3의 유도체입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1235481-90-9
Sample solution is provided at 25 µL, 10mM.
Product has been cited by 1 publications
Product Documents
Quality Control & SDS
- View current batch:
- Purity: >98.50%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
P7C3-A20 is a derivative of P7C3 with potent neuroprotective activity.
References:
[1]. Blaya MO et al. Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury.J Neurotrauma. 2014 Mar 1;31(5):476-86.
[2]. Walker AK et al. The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasinghippocampal neurogenesis. Mol Psychiatry. 2015 Apr;20(4):500-8.
| Cas No. | 1235481-90-9 | SDF | |
| Canonical SMILES | FC(CNC1=CC(OC)=CC=C1)CN2C3=CC=C(Br)C=C3C4=CC(Br)=CC=C24 | ||
| Formula | C22H19Br2FN2O | M.Wt | 506.21 |
| Solubility | DMSO : ≥ 100 mg/mL (197.55 mM);Water : < 0.1 mg/mL (insoluble) | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
Complete Stock Solution Preparation Table
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 1.9755 mL | 9.8773 mL | 19.7546 mL |
| 5 mM | 0.3951 mL | 1.9755 mL | 3.9509 mL |
| 10 mM | 0.1975 mL | 0.9877 mL | 1.9755 mL |
In vivo Formulation Calculator (Clear solution)
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Related Products
- GC38375 Remibrutinib
- GC35867 DiosMetin 7-O-β-D-Glucuronide
- GC42773 AM1248
- GC12333 BV6
- GC31312 RCGD423
- GC35384 Argatroban monohydrate
- GC36160 Glycerol derivative 1
- GC41823 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)
- GC15333 A 844606
- GC12209 5-fluoro 203
- GC39444 Solvent Yellow 16
- GC40616 Des-4-fluorobenzyl Mosapride
- GC19367 UNC1079
- GC33016 MP-A08
- GC43964 JWH 081 2-methoxynaphthyl isomer
- GC61321 Terminolic acid
리뷰
Average Rating: 5 ★★★★★ (Based on Reviews and 2 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *