Paeoniflorigenone |
| Catalog No.GC61799 |
Moutan cortex의 뿌리에서 유효성분으로 분리된 Paeoniflorigenone은 암세포주에서 선택적으로 apoptosis를 유도하여 항증식 효과를 나타낸다.
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Cas No.: 80454-42-8
Sample solution is provided at 25 µL, 10mM.
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Paeoniflorigenone, isolated as an active ingredient from the root of moutan cortex, induces apoptosis selectively in the cancer cell lines and exhibits antiproliferative effect[1].
Paeoniflorigenone (0-30 μM; 0-72 hours) significantly decreases the cell proliferation of tumor cell lines and inhibits the proliferation of normal cell lines[1].Paeoniflorigenone (0-30 μM; 24-72 hours) significantly induces apoptotic DNA fragmentation selectively in tumor cells[1]. Cell Proliferation Assay[1] Cell Line: TIG-1, 3T3-L1, HL60, Jurkat and HeLa cells
[1]. Huang Y, et al. Apoptosis-inducing activity and antiproliferative effect of Paeoniflorigenone from moutan cortex. Biosci Biotechnol Biochem. 2017;81(6):1106-1113.
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