>>Signaling Pathways>> DNA Damage/DNA Repair>> DNA/RNA Synthesis>>Phen-DC3

Phen-DC3

Catalog No.GC30695

Phen-DC3은 각각 65±6 및 50±10nM의 IC50으로 FANCJ 및 DinG 헬리카제를 억제할 수 있는 G-사중체(G4) 특이적 리간드입니다.

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Phen-DC3 Chemical Structure

Cas No.: 942936-75-6

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.

[1]. Bharti SK, et al. Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem. 2013 Sep 27; 288(39):28217-29.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 20 reference(s) in Google Scholar.)

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