PK150 |
| Catalog No.GC39300 |
Sorafenib의 유사체인 PK150은 submicromolar 농도에서 여러 병원성 균주에 대한 경구 생체이용률 및 항균 활성을 나타냅니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2165324-62-7
Sample solution is provided at 25 µL, 10mM.
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PK150, an analogue of Sorafenib, shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 µM, respectively[1].
[1]. Le P, et al. Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms. Nat Chem. 2019 Dec 16.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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