Praliciguat (Synonyms: IW-1973) |
| Catalog No.GC65449 |
Praliciguat(IW-1973)는 강력하고 경구 활성인 가용성 구아닐레이트 사이클라제 자극제로 NO 신호 전달을 강화하고 혈관 확장제 역할을 합니다.
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Cas No.: 1628730-49-3
Sample solution is provided at 25 µL, 10mM.
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Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM[1].
[1]. Daniel P Zimmer, et al. Abstract 16938: IW-1973 is a Potent Soluble Guanylate Cyclase Stimulator in vitro and in vivo With Extensive Tissue Distribution.
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