Praliciguat (Synonyms: IW-1973) |
| カタログ番号GC65449 |
Praliciguat (IW-1973) は、強力で経口的に活性な可溶性グアニル酸シクラーゼ刺激剤であり、NO シグナル伝達を増強し、血管拡張剤として作用します。
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Cas No.: 1628730-49-3
Sample solution is provided at 25 µL, 10mM.
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Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM[1].
[1]. Daniel P Zimmer, et al. Abstract 16938: IW-1973 is a Potent Soluble Guanylate Cyclase Stimulator in vitro and in vivo With Extensive Tissue Distribution.
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