>>Signaling Pathways>> PI3K/Akt/mTOR Signaling>> PDK-1>>PS47

PS47

Catalog No.GC63155

PS47은 PS48의 비활성 E-이성질체입니다.

Products are for research use only. Not for human use. We do not sell to patients.

PS47 Chemical Structure

Cas No.: 1180676-33-8

Size 가격 재고 수량
5 mg
US$72.00
재고 있음
10 mg
US$115.00
재고 있음
25 mg
US$230.00
재고 있음
50 mg
US$368.00
재고 있음
100 mg
US$590.00
재고 있음

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Based on customer reviews.

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48[1][2].

PS47 shows very low binding affinity or no binding to PDK1 (Kd>200 µM)[1].

[1]. Hindie V, et, al. Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol. 2009 Oct;5(10):758-64.
[2]. Pastor-Flores D, et, al. PIF-pocket as a target for C. albicans Pkh selective inhibitors. ACS Chem Biol. 2013 Oct 18;8(10):2283-92.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 37 reference(s) in Google Scholar.)

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