(R)-Lanicemine |
| Catalog No.GC61847 |
(R)-Lanicemine((R)-AZD6765)은 Lanicemine의 덜 활성인 R-거울상 이성질체입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 190581-71-6
Sample solution is provided at 25 µL, 10mM.
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(R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 µM for NMDA receptor; IC50s of 4-7 µM and 6.4 µM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects[1].
References:
[1]. Sanacora G, et al. Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacywith minimal psychotomimetic adverse effects. Mol Psychiatry. 2014 Sep;19(9):978-85.
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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