S26131 |
Catalog No.GC38844 |
S26131(화합물 5)은 강력하고 선택적인 MT1 멜라토닌성 리간드이며, Ki 값은 MT1 및 MT2에 대해 각각 0.5 및 112 nM입니다.
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Cas No.: 296280-56-3
Sample solution is provided at 25 µL, 10mM.
S26131 (compound 5) is a potent and selective MT1 melatoninergic ligand, and the Ki values are 0.5 and 112 nM for MT1 and MT2, respectively. S26131 behaves as an MT1 and MT2 antagonist[1].
S26131 behaves as an antagonist on MT1 and MT2 receptors with KB values of 5.32 and 143 nM, respectively[1].
[1]. Descamps-FranÇois C, et al. Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands. J Med Chem. 2003 Mar 27;46(7):1127-9.
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